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Hepatitis C: Diagnosis and Treatment

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Hepatitis C is a very important viral illness that primarily get a new liver. Latest estimates indicate that about 1-2% of U.S. human population are suffering from this illness. It is one of the most frequent reasons for chronic liver condition, bringing about hardening and cancer with the liver. Unsurprisingly, hepatitis C remains just about the most common indications for liver transplant surgery in america.

Normally, hepatitis C virus is transmitted through blood products. Therefore, hepatitis C is contracted from items which are contaminated with blood for example needles and IV drugs. However, herpes rarely is in transmitted by casual contact, or from food. Furthermore, unlike hepatitis B, hepatitis C is never trasmitted from sexual contact. Unfortunately, there isn't any effective kind of vaccination for hepatitis C.

Hepatitis C is often a chronic viral illness in which the infection lasts longer at least A few months in duration. Generally, patients with chronic hepatitis C infection don't have knowledge of their illness, because symptoms related to this condition is rare ahead of time. However, as the viral infection persists, individuals may turn to see persistent and chronic lassitude (fatigue). Others may complain of anorexia, nausea, as well as weight loss in rare cases. Since the illness advances, there can be findings including yellowing of the skin (jaundice), vomiting of blood (hematemesis), fluid within the abdomen (ascites), and altered a higher level consciousness and confusion (encephalopathy). However, a lot more worrisome complication of chronic hepatitis C is the occurrence of cirrhosis or even the hardening of liver, and liver cancer, referred to as hepatocellular carcinoma (hepatoma).



Hepatitis C is diagnosed using blood tests. The first task in the diagnosis include hepatitis C antibody (ELISA based), and liver function test (ALT/AST). If the antibody is detected, hepatitis C viral RNA test will look at the active infection. For cases of hepatitis C confirmed with viral RNA, additional tests which can be often necessary include genotyping, alpha-feto-protein (AFP), a serum marker for liver cancer, and ultrasound of the liver. Finally, a liver biopsy could possibly be obtained to totally characterize the overall condition of the liver disease also to exclude presence of fibrosis (cirrhosis).

Treatments alternatives for hepatitis C is rapidly evolving. Available today treatments include ribavirin, PEG-interferon, and protease inhibitor like telaprevir and boceprevir. For patients with genotype 1 hepatitis C, a triple mixture of ribavirin, interferon, and protease inhibitor is usually recommended for 6-12 months. They could expect cure rate of around 70%. However, patients with genotype 2 and 3 are treated for 6 months with a dual regimen of interferon and ribavirin. They have a higher cure rate of 80-90%.

Chronic hepatitis C is a very serious condition. For people using this type of illness, it is crucial which they undergo a consistent check-up including periodic liver function test, AFP determination, and sonogram. Additionally it is far better to avoid alcohol, and then for any unnecessary medication. For individuals with active viral replication, the procedure with anti-viral drugs is recommended to prevent potential complications including cirrhosis and hepatoma.

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